Injury Report: Rams vs. 49ers

Rams Update

The Rams will be without several key players on Sunday when they take on the 49ers. Quarterback Matthew Stafford is out with a concussion, and wide receiver Cooper Kupp is also out with an ankle injury.

Other Rams players who are questionable for the game include running back Cam Akers (ankle), tight end Tyler Higbee (knee), and offensive tackle Rob Havenstein (knee).

49ers Update

The 49ers are also dealing with some injuries heading into Sunday's game. Wide receiver Deebo Samuel is questionable with a hamstring injury, and running back Elijah Mitchell is also questionable with a knee injury.

Other 49ers players who are out for the game include quarterback Trey Lance (ankle), wide receiver Jauan Jennings (ankle), and defensive end Nick Bosa (knee).

Fantasy Impact

The injuries to Stafford and Kupp are a major blow to the Rams' offense. Stafford is one of the best quarterbacks in the NFL, and Kupp is one of the best wide receivers.

The injuries to Samuel and Mitchell are also a major blow to the 49ers' offense. Samuel is one of the most versatile players in the NFL, and Mitchell is one of the best young running backs.

Fantasy owners who have players from either team should be prepared to make some lineup changes for Sunday's game.

Conclusion

The Rams and 49ers are both dealing with some key injuries heading into Sunday's game. The injuries could have a major impact on the outcome of the game, so fantasy owners should be prepared to make some lineup changes.